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Geographic Focus
Pearl Street Venture Funds will invest mainly in companies located in Indiana. Historically underserved by the venture capital community, Indiana is home to a number of major research institutions and has the 5th largest life sciences industry cluster in the nation.

Area of Expertise
The investment should be within our focus and one, or more, of the partners should have experience directly relevant to the proposed field of activity. Our partners use their extensive experience and hands-on approach to mentor portfolio companies in every aspect of their businesses, from basic science through the ultimate exit. Our portfolio companies will have the advantage of investors who can help guide important decisions, assemble proper management teams, initiate and shape key customer and partner relationships; and provide counsel on finance, acquisition and exit strategies.

Market Opportunity
Successful companies address genuine market needs. The market should be specific, large, and growing or changing rapidly. It should have no barriers to high profitability. In order to translate strong science into a viable business, companies must offer a compelling value proposition to larger industry players representing potential exit opportunities. Business models must be realistically based on an extensive understanding of the business and scientific needs of this complex group of customers, and must be in good alignment with the system for reimbursement of medical costs. We conduct a comprehensive, competitive and technical analysis to confirm that the company is likely to be able to become a leader in its industry.

Proprietary or Strategic Position
The "keys to success" of the company should be unique and suitable for protection, either through patents or in other ways. Beyond intellectual property protection, we look for the ability to build meaningful barriers to competition through speed, scale or know-how that cannot easily be surmounted. In this business, the difference between success and failure often hinges on key decisions regarding intellectual property, licensing, partnering and regulatory matters. These decisions strongly influence competitive position, revenue potential and time to market, all key determinants of success.

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