A discovery platform technology focused on APE1/Ref1 pathway to produce a series of novel compounds for cancer treatment. http://apextherapeutics.com


FDA clean room monitoring technology in pharmaceutical and homeland security - Sold Yamatake Corporation





An innovative biotechnology company focusing on therapies for central nervous system (CNS) disorders. The company’s lead compound is designed to deliver efficacy in migraine without the vasoconstrictor activity associated with previous generations of migraine therapy. In addition, the company is developing a rich pipeline of novel chemical entities (NCEs) for therapy of sleep/wake disorders, chronic pain, Alzheimer’s disease and psychiatric disorders.


A unique catheter based technology to size and place stents utilizing novel impedance technology. The devices are suitable for peripheral and cardiac applications.




A discovery platform technology based on an immuno-modulatory compound that can stimulate or suppress the autoimmune system.






A small molecule HSP90 inhibitor discovery platform technology for the treatment of cancer – Sold to Pfizer, Inc.